Which antibiotics are used to treat prostatitis?

In some cases, antibiotics are included in the treatment regimen for prostatitis. The choice of a particular drug depends on many factors. There are many significant differences in antimicrobial therapy for acute and chronic disease.

Taking antibiotics is an important part of the successful treatment of acute and chronic prostatitis. The success of treatment depends largely on the correct choice of drugs and their dosing regimen.

Indications for the appointment and effect of antibiotics for prostatitis

Antibiotics are prescribed when prostate inflammation is clearly caused by an infection. This applies not only to the acute course of the disease, when obvious symptoms compel emergency assistance. Chronic bacterial prostatitis, with mild or no symptoms, also requires antibiotic treatment.

The indication for taking antibiotics is not some specific symptoms, but laboratory data indicating the presence of an infection.

To do this, use PCR (polymerase chain reaction), which can identify infections transmitted through sexual contact with high precision, and studies of urine and prostate secretions, which can detect the presence of bacteria.

Sometimes infectious inflammation can hide - in this case, the level of white blood cells in glandular secretions does not exceed normal levels. To determine if an infection is present, doctors will prescribe test doses of antibiotics. After taking the drug for a week, the analysis is performed again, and if the white blood cell level is above 25 units, we are talking about the hidden process of prostatic infectious lesions. In this case, antibiotics become mandatory.

The choice of antibiotics to treat prostate inflammation depends on several factors. The key is which bacteria have been identified and which drugs they are susceptible to. There is no one-size-fits-all cure.

How antibiotics work depends on which drug is used, the form of the disease, and the causative agent of the inflammation. However, the general essence can be reduced to several stages:

  1. The drug penetrates into the blood by assimilation in the gastrointestinal tract or by intravenous administration.
  2. Active substances penetrate into the prostate tissue and destroy the pathogens of the disease.
  3. The effects build up in the glandular tissue so you can keep fighting off infections.

This last step is especially important because some antibiotics are only bacteriostatic. This means they only affect dividing cells. Meanwhile, those cells in an anaerobic state remained unnoticed by them. If the active substances of the drug do not accumulate in the prostate tissue, the bacteria leaving the anaerobic state will quickly negate the entire effect of the treatment.

Some bacteria are highly resistant to drugs. These are probably the most common pathogens of prostatitis, such as E. coli. They manufacture hard capsules and biofilms to reduce the effects of active pharmaceutical ingredients. In this case, the drug must have the ability to disrupt the protective shell of these bacteria. It is important to take the medicine until the end, even if the symptoms of the disease have gone away.

Group of antibiotics for the treatment of prostatitis

There are several groups of antibiotics that are effective (alone or in combination) against the bacteria that cause inflammation of the prostate. The choice of a particular drug group depends on many factors: the "weakness" in the identified bacteria, the patient's comorbidities, the severity of the prostatitis course, its form and the side effects of the drug.

The main antibacterial drugs used to treat prostatitis include:

  • tetracycline;
  • penicillin;
  • cephalosporins;
  • macrolides;
  • Fluoroquinolones.

Tetracycline series

This group of antibiotics is bacteriostatic, which means they prevent cell division, growth and development.

Don't assume that bacteriostatic drugs are unequivocally ineffective. This effect is sufficient to eliminate the infection as long as the patient's immunity is not compromised.

Such drugs disrupt the connections between RNA (which "issues commands" for pathogens to develop and divide) and ribosomes (which carry out those "commands"), thereby inhibiting the production of proteins - the building blocks of new cells.

Man taking antibiotics for prostatitis

This group of drugs is effective against the following pathogens:

  • Mycoplasma;
  • Ureaplasma urealyticum;
  • Chlamydia;
  • Enterococcus;
  • Enterobacter;
  • Klebsiella;
  • Pseudomonas;
  • jagged;
  • Escherichia coli.

Drugs in this group are prescribed selectively due to a large number of side effects.

Penicillin series

This group of preparations also has bacteriostatic effect and affects dividing bacteria. However, they work differently: They block the production of peptidoglycan, the main component of bacterial cell walls.

Since many bacteria in this group developed resistance to antibiotics, a protected subgroup of penicillin was developed.

These antibiotics are effective in treating inflammation caused by the following bacteria:

  • Neisseria gonorrhoeae;
  • staphylococcus;
  • Enterobacter;
  • Proteus;
  • Klebsiella;
  • jagged;
  • Escherichia coli.

Due to the high risk of allergic reactions, the drugs in this group are prescribed with caution. To treat prostate inflammation, drugs based on oxacillin, ampicillin and amoxicillin are prescribed.


These are powerful bactericidal drugs that not only prevent cells from dividing, but destroy them. This occurs in two steps: disruption of peptidoglycan production (disruption of the cell wall) and release of enzymes.

This group of drugs is effective against the following diseases:

  • Neisseria gonorrhoeae;
  • Enterobacter;
  • Proteus;
  • Klebsiella;
  • Escherichia coli.

This group of drugs includes drugs based on ceftriaxone, cephalosporins, and cefpirone.


A group of the safest antibiotics with the fewest side effects. They work by stopping the production of proteins that cells build. The effect (bactericidal or bacteriostatic) depends on the choice of drug and its concentration in the body.

Annotation of a man working on a prostatitis antibiotic

Antibiotics in this group are effective against the following bacteria:

  • Neisseria gonorrhoeae;
  • Chlamydia;
  • Ureaplasma urealyticum;
  • Mycoplasma.

Not all physicians in this group prescribe drugs for prostatitis because, although it can be assumed that their effect is logical, there has been no narrow research on this topic. This group of drugs includes azithromycin- and clarithromycin-based drugs.


These are not antibiotics in the classical sense, as antibiotics are drugs of natural origin or their closest synthetic counterparts. Fluoroquinolones have no analogues in nature.

This particular group of drugs is most often prescribed by urologists. There are good reasons for this:

  • First, they have a very broad bactericidal effect, comparable to natural antibiotics with fewer side effects.
  • Second, they have a very active antibacterial effect: they affect both the production of DNA, preventing its replication, but also topoisomerases (an important part of viral integration into cells), as well as RNA, as well as cell membrane walls and other processes that ensure vital activityAnd the process of cell division - such a massive attack from all sides with good effect.

Fluoroquinolones are effective against:

  • Intestinal and Pseudomonas aeruginosa;
  • staphylococcus;
  • Neisseria gonorrhoeae;
  • Mycoplasma;
  • Chlamydia and other bacteria.

This group of antibiotics is used in the complex treatment of Kochella spp. So before you start taking these medicines, it's important to make sure you don't have the TB causative agent in your body. The fact that ingesting fluoroquinolones alone can help Koch rods develop resistance to other antibiotics makes the process of treating TB more complicated.

Most Effective Antibiotics for Prostate Inflammation

Even the most effective antibiotics will be useless or even harmful if the reason for choosing this drug is advertising, the opinions of incompetent people who are helped by it, or the fact that the drug worked last time. There is no medicine that works against all bacteria and viruses, but each group of antibiotics has its best representatives.

General principles and characteristics of antibiotic therapy for acute and chronic prostatitis

The choice of treatment options and medications depends on the form of prostatitis. The treatment of acute and chronic prostatitis has both similarities and differences.

For antibiotic treatment of any type of prostatitis, the following aspects are characteristic:

  • A doctor must be contacted and tested to identify the pathogen;
  • Treatment should continue as planned, even if it appears to have recovered completely.

At the same time, there are a few different factors to consider when choosing a drug to treat inflammation. Therefore, for the treatment of chronic prostatitis, the ability of active substances to penetrate into prostate cells is crucial. It has been shown that high concentrations of the drug in the blood alone are not enough. Not all broad-spectrum drugs, even the latest generation, have this ability. When it comes to acute inflammation, the situation is different: it increases the permeability of prostate cells, allowing drugs to enter from the bloodstream.

The ability of drugs to penetrate and accumulate in tissues is critical in chronic inflammation but less so in acute inflammation.

The second difference is that, given the severity of the condition, the acute phase should be treated as soon as possible. Therefore, bactericidal drugs (fluoroquinolones) are preferred over bacteriostatic drugs. Where the mechanism of action of the drug depends on the dose, the concentration of the drug in the blood and prostate should be sufficient to maintain the bactericidal effect - this applies to macrolides.

Choose bacteriostatic antibiotics for chronic inflammation and bactericidal antibiotics for acute inflammation.

Natural antibiotics: effectiveness and methods of application

Considering that almost all antibiotics are of natural origin (or their closest analogues), it is reasonable to assume that herbal remedies have similar effects, with better tolerance and fewer side effects.

However, if the effect of the herb is sufficient, there is no need to produce the drug. Therefore, herbal remedies with antibacterial properties are only suitable as an adjunctive treatment or preventive measure for chronic inflammation of the prostate.

There are several herbs that fight bacteria:

  • Yarrow (bactericidal and bacteriostatic effect on Escherichia coli and Enterobacter);
  • Absinthe (effective against Escherichia coli and Pseudomonas aeruginosa);
  • eleutherococcus (against Staphylococcus aureus, Escherichia coli and Enterobacter);
  • Plantain large (against Staphylococcus albus, Enterobacter, antibacterial effect on Proteus, has analgesic effect).

There are many recipes that can be used to prepare antibacterial drugs to relieve inflammation. It is best to prepare infusions from herbs that do not require prolonged exposure to temperature.

Herbal soup as a natural antibiotic for prostatitis

For almost any herb, the following recipes will work:

  1. Take one part herb and ten parts water at room temperature.
  2. The mixture was heated in a boiling water bath for a quarter of an hour.
  3. Infuse for 45 minutes.
  4. Pass a filter such as gauze.

Infusions are most effective if taken immediately after preparation.

In addition, to combat prostatitis, hazel, poplar and chestnut bark are used. Decoctions are best prepared from these materials. Each plant has its own recipe, but in general, the decoction is prepared as follows:

  1. Wash and grind raw materials.
  2. Put in water so that it completely covers the branches or bark.
  3. Cook in a water bath for half an hour.
  4. Cool for 10 minutes, drain the broth and squeeze the stock.

Broth can be taken within 2 days from the date of preparation.

The effectiveness of the treatment depends on several factors: the choice of the required natural antibiotics, the availability of high-quality raw materials (preferably prepared by yourself) and the correct preparation of the infusion or decoction.

The choice of antibiotic for prostatitis depends on the infection causing the inflammation, the form of the disease, and the patient's general health. Each drug has contraindications and side effects, so you should consult a urologist before taking it. The same applies to herbs that have antibacterial properties.